External Projects:
Collaborative Projects (CPs)
CPs should address substantial technical challenges in the field of Tissue Manufacturing. They should target issues difficult to solve with current approaches and help to drive the development of new technologies..
CPs are expected to be externally funded prior to beginning work.
Existing Collaborative Projects

- Investigator & Institution: Kevin Healy, Ph.D., University of California – Berkeley, Berkeley, CA
- Title: Non-destructive assessment of cryopreserved microtissues post-thaw.
- Funding Source: NSF
- Investigator & Institution: John Moore, B.A., Scientific Bioprocessing, Inc., Pittsburgh, PA
- Title: Real-time nutrient and metabolite monitoring during cell and tissue culture for quality engineering of tissue-engineered medical products
- Funding Source: Scientific Bioprocessing, Inc. corporate funds
- Investigator & Institution: Alexander Revzin, Ph.D., Mayo Clinic, Rochester, MN
- Title: Bioreactor culture of hPSC spheroids for pancreatic β cells
- Funding Source:Kieckhefer Foundation
- Investigator & Institution: George Christ, Ph.D., University of Virginia, Charlottesville, VA
- Title: Evaluation of novel, non-invasive CQAs for biomanufacturing of TEMPs in a modular, closed-loop bioreactor system
- Funding Source: NIH, DOD
- Investigator & Institution: Peter Alexander, Ph.D., Hang Lin, Ph.D., University of Pittsburgh, Pittsburgh, PA
- Title: Bioreactor control of tissue-chip models for synovial joint pathologies
- Funding Source: NIH
- Investigator & Institution:Aaron Haubner, Celartia, Inc., Columbus, OH
- Title: Developing novel strategies for shipping and storing Tissue-Engineered constructs at room temperature
- Funding Source: Corporate funds
- Investigator & Institution: Elizabeth Lipke, Ph.D., Auburn University, Auburn AL
- Title:RECODE: Directing and Controlling Cardiac Differentiation Through Cellular and Microenvironmental Manipulation and Application of Machine-Learning
- Funding Source: NSF
- Investigator & Institution:Julia Oxford, Boise State University, Boise, ID
- Title: Optimization of the MSC-responsive chondrogenic phenotype towards articular chondrocytes
- Funding Source: NIH
- Investigator & Institution: Dimitrios Kouroupis, Ph.D., University of Miami, FL
- Title: Mesenchymal Stem Cell Functionalization in 3D Manufacturing Settings for Clinical Applications
- Funding Source: Department start-up funds
- Investigator & Institution: Sam Senyo, Ph.D., Case Western Reserve University, Cleveland, OH
- Title: Cardiomyocyte differentiation by combinatorial paracrine signaling
- Funding Source: Startup and NIH
- Investigator & Institution: Riccardo Gottardi, Ph.D., Children Hospitals of Philadelphia, PA
- Title: Bioinstructive reactors for mechanical conditioning of tissues
- Funding Source: Startup funds
- Investigator & Institution:Tomás Egaña, SYMBIO2 Inc. and Pontificia Universidad Católica de Chile, Santiago, Chile
- Title: Transplant organ preservation
- Funding Source:SYMBIO2 Inc. Corporate funds
- Investigator & Institution: Eben Alsberg, Ph.D., University of Illinois, Chicago, IL
- Title: Opposing RNAi molecule gradient constructs to repair osteochondral defects
- Funding Source: Startup funds
- Investigator & Institution: Aldo Leal-Egana, Ph.D., University of Heidelberg, Germany
- Title: Bone osteotropism: Influence of confinement and mechanical properties of the seeds in the selection of the soil
- Funding Source: LE-3418/4-1
- Investigator & Institution: Aldo Boccacini, Ph.D., University of Erlangen-Nuremberg, Institute of Biomaterials, Erlangen, Germany
- Title:Bioactive Glass-derived scaffolds for bone tissue engineering.
- Funding Source:Institute of Biomaterials internal funds
- Investigator & Institution:Carolyn Schutt Ibsen, Ph.D., Oregon Health & Science University, Portland, Oregon
- Title: Energy-responsive biomaterial platforms for regenerative medicine
- Funding Source: Department Start-Up funds
- Investigator & Institution: Yolanda Fortenberry, Case Western Reserve University, Cleveland, OH
- Title: Developing tissue-specific aptamers
- Funding Source:Department of Biology startup funds
- Investigator & Institution: Rhima Coleman, Ph.D., University of Michigan, Ann Arbor, MI
- Title: Identification of –omics signatures related to the chondrogenic potential of hMSC
- Funding Source: NIH/NSF
- PI & Institution: Weiqiang Chen, PhD, Cleveland Clinic Foundation
- Title: Mechanistic insights into joint formation dysregulation by human viral pathogens
- Funding Source: NIH 4R01DE028573
Interested in initiating a new collaborative project?